University of Chicago
The University of Chicago is internationally renowned as a leader in Cancer Immunology and Developmental Therapeutics, with research programs ranging from basic scientific investigation to Phase I, II, and III clinical trials. The Section of Hematology/Oncology in the Department of Medicine has a proud and long history of excellence in advancing cancer care through basic and translational discovery.
About the Department
The Research Professional will lead cancer immunology projects in the Sweis laboratory (sweislab.org). The laboratory is investigating mechanisms of cancer immunotherapy resistance, through the use of cutting-edge bladder cancer and skin cancer model systems. The position requires the ability to perform tasks independently and lead small groups within the lab on projects. Collaborations with other laboratories and investigators within the Section and Department are routine.
With respect to laboratory technical skills, the individual must be proficient in cell/tissue culture, flow cytometry/sorting (FACS), protein isolation and analysis (western blot, ELISA, and immunohistochemistry), RNA isolation and analysis by qRT-PCR, molecular biology (PCR, genotyping, cloning plasmid constructs, DNA isolation and sequencing analysis, CRISPR). Knowledge of cancer immunology and advanced experimental techniques such as single cell RNAseq or special transcriptomics is preferred. The individual must be comfortable with mouse modeling (husbandry/breeding, genotyping, surgical procedures, drug administration by oral gavage, intraperitoneal and tail vein injection harvest, protein, RNA and immunohistochemical analysis).
The professional will also be expected to train new members of the laboratory. Finally, the candidate will be expected to generate manuscripts, formulate grant proposals, and present research at major conferences.
Molecular biology - PCR, genotyping, cloning plasmid constructs, DNA isolation and sequencing analysis.
Cell culture - in vitro experiments, retroviral transductions, CRISPR.
Mouse work – maintenance of colonies, running experiments in mice.
Immunoassays: Flow cytometry (FACS), ELISPOT, ELISA.
Advanced experimental techniques (single cell sequencing, spatial transcriptomics).
Collate and analyze data.
Maintain accurate, up-to-date and well-documented records of procedures performed and data generated.
Summarize results, assist in interpreting findings, and generate manuscripts and grants.
Instruct new personnel including technologists, residents, medical students, or fellows.
Collaborates on development of new research projects with academic and community-based organizations.
May present work at scientific meetings.
Performs other related work as needed.
Education:Minimum requirements include a PhD in related field.
Doctoral degree in Cancer Biology or Cancer Immunology or related discipline.
Prior biology/immunology laboratory experience.
The ability to work as part of a team and to be open minded and cooperative.
The ability to apply new concepts and have a creative approach to problem solving.
Excellent verbal and written communication skills.
The ability to organize your own work with minimal supervision and prioritize in response to deadlines.
Cover Letter (preferred)
When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.
Scheduled Weekly Hours
Drug Test Required
Health Screen Required
Motor Vehicle Record Inquiry Required
The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, national or ethnic origin, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.
Staff Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.
We seek a diverse pool of applicants who wish to join an academic community that places the highest value on rigorous inquiry and encourages a diversity of perspectives, experiences, groups of individuals, and ideas to inform and stimulate intellectual challenge, engagement, and exchange.
All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.
The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: http://securityreport.uchicago.edu. Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.