Research Scientist

University of Chicago

University of Chicago

Chicago, IL, USA
Posted on Friday, October 27, 2023


BSD SRF – Proteomics

About the Department

The Proteomics Platform at the University of Chicago is a research facility located in the Knapp Center for Biomedical Discovery (KCBD). The mission of the facility is to develop and apply advanced proteomics techniques to answer both basic and translational scientific questions with the help of state-of-the-art mass spectrometry instruments. We offer scientific consultation tailored to each project, proteomics sample preparation services, and education to help researchers design, perform, and interpret complex proteomics data. We aim to support both the University of Chicago research community and beyond.

Job Summary

The University of Chicago's Proteomics Platform is seeking a Research Scientist to play a pivotal role in driving advanced proteomics research using our suite of next-gen Orbitrap instruments. The selected individual will also be instrumental in maintaining laboratory instruments, preparing samples, and conducting quantitative proteomics experiments. This position offers a unique opportunity to delve into the fast-evolving field of proteomics, working with some of the most cutting-edge equipment available today. In addition, the Research Scientist will gain expertise in various proteomics techniques and become proficient in data analysis software essential for diverse proteomics projects.

The job performs routine assignments related to scientific research projects. Ensures compliance of research activities with institutional, state, and federal regulatory policies, procedures, directives and mandates. Analyzes possible solutions using standard procedures. Writes articles, reports and manuscripts. Assists in drafting presentations on research findings.


  • Diligently perform routine laboratory maintenance tasks and engage in proteomics sample processing, method development, and optimization to ensure the lab's research activities run efficiently.

  • Execute LC-MS/MS and other mass spectrometry techniques with precision, producing quantitative global and targeted proteomics data.

  • Collaborate with investigators to align on research objectives and ensure data relevance for a diverse range of projects.

  • Participates in scientific discussions and brainstorming regarding experimental design, and new technological development and innovation around various research themes requiring proteomics.

  • Stay updated with the latest techniques, tools, and advancements in the proteomics domain and actively seek opportunities for training and skill enhancement to contribute effectively to the platform's research initiatives.

  • Maintains technical and administrative support for a research project.

  • Analyzes and maintains data and/or specimens. Conducts literature reviews. Assists with preparation of reports, manuscripts and other documents.

  • Installs, sets up and performs experiments; interacting with students and other laboratory staff under the direction of the principal investigator.

  • Performs other related work as needed.

Minimum Qualifications


Minimum requirements include a college or university degree in related field.

Work Experience:

Minimum requirements include knowledge and skills developed through < 2 years of work experience in a related job discipline.



Preferred Qualifications


  • Bachelor's degree in biology, chemistry or field of study related to the research of the laboratory.


  • Hands-on experience with Orbitrap mass spectrometry instruments is highly desirable. Candidates have contributed to or led multiple projects utilizing these instruments.

  • Proven track record in a mass spectrometry-based research laboratory, with evidence of contributions to research projects, publications, or presentations.

  • Experience working collaboratively with multidisciplinary teams, including researchers, technicians, and external collaborators.

  • Proficiency in using data analysis software for proteomics or related field and experience interpreting complex datasets.

  • Experience working in a research laboratory or core facility.

  • Experience working within a mass spectrometry-based research laboratory.

Preferred Competencies

  • Demonstrated understanding and proficiency in proteomics and related scientific methodologies.

  • Ability to foster strong relationships with colleagues, collaborators, and stakeholders. Comfortable working in a service and collaborative-oriented environment and building interdisciplinary collaborations.

  • Ability to analyze complex scientific data, troubleshoot experiments, and devise innovative solutions to research challenges.

  • Advanced skills in using scientific software and tools for proteomics or related field research.

  • Competence in maintaining accurate and detailed electronic records.

  • Excellent written and verbal communication skills.

  • Flexibility and willingness to learn new technologies.

  • Ability to contribute to research projects with minimal guidance while also collaborating effectively as part of a team.

  • Proven skills in managing multiple projects simultaneously, prioritizing tasks effectively, and meeting research milestones and deadlines.

  • Ability to be on-time for scheduled appointments and adapt to unscheduled requests.

Working Conditions

  • May require training related to occupational safety and health, environmental compliance (working with heavy metals), shipping of hazardous material (shipping cryo-samples).

  • Working at a desk or sitting at a microscope.

  • Ability to go up and down stairs.

  • Ability to move wheeled LN2 tanks.

Application Documents

  • Resume (required)

  • Cover Letter (preferred)

When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.

Job Family


Role Impact

Individual Contributor

FLSA Status


Pay Frequency


Scheduled Weekly Hours


Benefits Eligible


Drug Test Required


Health Screen Required


Motor Vehicle Record Inquiry Required


Posting Statement

The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, national or ethnic origin, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.

Staff Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.

We seek a diverse pool of applicants who wish to join an academic community that places the highest value on rigorous inquiry and encourages a diversity of perspectives, experiences, groups of individuals, and ideas to inform and stimulate intellectual challenge, engagement, and exchange.

All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.

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